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VOLUME 38 (1983) | ISSUE 9 | PAGE 424
Nonlinear laser cutting of RNA which is selective in terms of the set of bases
A chromophore (dansyl) has been chemically attached to a small DNA fragment (an oligonucleotide) (ρ T}9. In the presence of this compound, synthetic RNA molecules can be cut by the beam from a nitrogen laser, and the cutting can be carried out selectively in terms of the set of bases of the RNA. The effect is attributed to a radiationless transfer to the RNA of the energy of a two-photon excitation of the bound dye.