Comparison of spiral waves in simplified cardiac tissue models
S. Mohanty, D. Prusty, A. R. Nayak
International Institute of Information Technology (IIIT) Bhubaneswar, 751003 Bhubaneswar, India
Abstract
Spiral waves of electrical activation in cardiac tissue can lead to
life-threatening arrhythmias; therefore, understanding the mechanisms
underlying the formation and propagation of these spiral waves is of
great
interest in cardiac dynamics. In this study, we conduct a comparative
analysis
of spiral waves using two simplified component models for cardiac tissue
(a)
the Panfilov model and (b) the Aliev-Panfilov
model, by varying the parameters that govern
excitability
and recovery in both models. From our numerical studies, we observe
states of
(i) a periodic spiral, (ii) a quasi-periodic spiral, and (iii) spiral
turbulence in both models, depending on the parameters. Our systematic
study
reveals that the Panfilov model exhibits conduction velocity restitution
behavior and spiral transition sequences that closely resemble those
observed
in biophysical models; thus, it is better suited for studying wave
dynamics in
cardiac tissue compared to the Aliev-Panfilov model, providing an
alternative
to computationally expensive cardiac tissue models.